Gene, protein, and tissue localization of human and rodent organic anion–transporting polypeptide (OATP/Oatp) isoforms
| Family | Human Gene | Human Protein | Tissue Expression | Rodent Gene | Rodent Protein | Tissue Expression |
|---|---|---|---|---|---|---|
| OATP1 | SLCO1A2 | OATP1A2 | Brain, kidney, liver, lung, testis, placenta | Slco1a1 | Oatp1a1 | Brain, liver, kidney |
| SLCO1B1 | OATP1B1 | Liver | Slco1a3 (rat only) | Oatp1a3 | Kidney | |
| SLCO1B3 | OATP1B3 | Liver, retina | Slco1a4 | Oatp1a4 | Brain, eye | |
| SLCO1C1 | OATP1C1 | Brain, testis | Slco1a5 | Oatp1a5 | Brain, eye, small intestine | |
| Slco1a6 | Oatp1a6 | Liver, eye | ||||
| Slco1b2 | Oatp1b2 | Brain | ||||
| Slco1c1 | Oatp1c1 | Brain, eye, testis | ||||
| OATP2 | SLCO2A1 | OATP2A1 | Ubiquitous | Slco2a1 | Oatp2a1 | Ubiquitous |
| SLCO2B1 | OATP2B1 | Liver, intestine, brain, heart, breast, placenta | Slco2b1 | Oatp2b1 | Brain, eye, liver | |
| OATP3 | SLCO3A1 | OATP3A1 | Brain, testis, heart, lung, spleen, peripheral blood, leukocytes, thyroid, breast | Slco3a1 | Oatp3a1 | Ubiquitous |
| OATP4 | SLCO4A1 | OATP4A1 | Ubiquitous | Slco4a1 | Oatp4a1 | Ubiquitous |
| SLCO4C1 | OATP4C1 | Kidney | Slco4c1 | Oatp4c1 | Kidney | |
| OATP5 | SLCO5A1 | OATP5A1 | Breast | |||
| OATP6 | SLCO6A1 | OATP6A1 | Brain, testis, spleen, placenta | Slco6b1 | Oatp6b1 | Testis, ovary, adrenal gland |
| Slco6c1 | Oatp6c1 | Testis | ||||
| Slco6d1 | Oatp6d1 | Unknown |