Characteristics of selected drug transporters
| Protein | Amino Acids | Direction | Family | Gene | Chromosome | Accession Number |
|---|---|---|---|---|---|---|
| P-gp | 1280 | Export | ABCB | ABCB1 | 7q21.12 | NM_000927 |
| BSEP | 1321 | Export | ABCB | ABCB11 | 2q24 | NM_003742 |
| MRP2 | 1545 | Export | ABCC | ABCC2 | 10q24 | NM_000392 |
| BCRP | 655 | Export | ABCG | ABCG2 | 4q22 | NM_004827 |
| MATE1 | 570 | Export | SLC47 | SLC47A1 | 17p11.2 | NM_018242 |
| MATE2-K | 602 | Export | SLC47 | SLC47A2 | 17p11.2 | NM_152908 |
| OATP1A2 | 670 | Uptake | SLC21/SLCO | SLCO1A2 | 12p12 | NM_134431 |
| OATP1B1 | 691 | Uptake | SLC21/SLCO | SLCO1B1 | 12p12 | NM_006446 |
| OATP1B3 | 702 | Uptake | SLC21/SLCO | SLCO1B3 | 12p12 | NM_019844 |
| OATP2B1 | 709 | Uptake | SLC21/SLCO | SLCO2B1 | 11q13 | NM_007256 |
| OCT1 | 554 | Uptake | SLC22 | SLC22A1 | 6q25.3 | NM_003057 |
| OCT2 | 555 | Uptake | SLC22 | SLC22A2 | 6q25.3 | NM_003058 |
| OCT3 | 556 | Uptake | SLC22 | SLC22A3 | 6q25.3 | NM_021977 |
| OAT1 | 563 | Uptake | SLC22 | SLC22A6 | 11q12.3 | NM_004790 |
| OAT2 | 546 | Uptake | SLC22 | SLC22A7 | 6p21.1 | NM_006672 |
| OAT3 | 542 | Uptake | SLC22 | SLC22A8 | 11q11 | NM_004254 |
| OAT4 | 550 | Uptake/efflux | SLC22 | SLC22A11 | 11q13.1 | NM_018484 |