Recommended warfarin starting dose in mg/day according to VKORC1 and CYP2C9 genotypes per the FDA-approved warfarin labeling
| VKORC1 -1639 | CYP2C9 | ||||
|---|---|---|---|---|---|
| *1/*1 | *1/*2 | *1/*3 or *2/*2 | *2/*3 | *3/*3 | |
| GG | 5–7 | 5–7 | 3–4 | 3–4 | 0.5–2 |
| AG | 5–7 | 3–4 | 3–4 | 0.5–2 | 0.5–2 |
| AA | 3–4 | 3–4 | 0.5–2 | 0.5–2 | 0.5–2 |