SEED | Plasmepsin (Friedman and Caflisch, 2009), target for malaria |
Flavivirus Proteases (Ekonomiuk et al., 2009a,b), target for WNV and Dengue virus |
Tyrosine kinase erythropoietin-producing human hepatocellular carcinoma receptor B4 (EphB4) (Lafleur et al., 2009) |
FlexX | Plasmepsin II and IV inhibitors (Luksch et al., 2008), malaria |
Anthrax edema factor (Chen et al., 2008) |
Pneumococcal peptidoglycan deacetylase inhibitors (Bui et al., 2011) |
Glide | Aurora kinases inhibitors (Warner et al., 2006) |
Falcipain inhibitors (Shah et al., 2011) |
Cytochrome P450 inhibitors (Caporuscioi et al., 2011) |
Surflex | Topoisomerase I, anticancer (optimization) |
DOCK | FK506 immunophilin (Zhao et al., 2006) |
BCL6, oncogene in B-cell lymphomas (Cerchietti et al., 2010) |