Association of β2-adrenoceptor variants with preterm labor and preterm birth
Data are an overview of candidate gene studies investigating ≥100 individuals.
| Variant | Number of Subjects | Population Origin | Variant Effect | Reference |
|---|---|---|---|---|
| Risk for spontaneous preterm birth | ||||
| c.46G>A (p.Gly16Arg) | 156 | Turkish | Gly = Arg | Ozkur et al. (2002) |
| 176 | Hungarian | Gly carriers < Arg | Doh et al. (2004) | |
| 279 | Hispanic | Gly carriers < Arg | Landau et al. (2002) | |
| c.79G>C (p.Gln27Glu) | 156 | Turkish | Gln < Glu carriers | Ozkur et al. (2002) |
| 176 | Hungarian | Gln = Glu | Doh et al. (2004) | |
| 279 | Hispanic | Gln = Glu | Landau et al. (2002) | |
| 549 | Australian | Gln < Glu | Gibson et al. (2007) | |
| Rate of cervical dilatation in term and late preterm active labor | ||||
| c.46G>A (p.Gly16Arg) | 103 | American | Gly = Arg | Reitman et al. (2011) |
| 401 | American | Gly > Arg | Miller et al. (2011) | |
| c.79G>C (p.Gln27Glu) | 103 | American | Gln < Glu | Reitman et al. (2011) |