Parameter (β-Blocker) | Number of Subjects | Population Origin | Variant Effect | Reference |
---|---|---|---|---|
Attenuation of exercise-induced HR and SBP increases (metoprolol) | 16 | Chinese | Arg > Gly | Liu et al. (2003) |
Attenuation of dobutamine-induced HR, contractility and PRA increases (bisoprolol) | 18 | German | Arg > Gly | Bruck et al. (2005b) |
Attenuation of exercise-induced tachycardia (esmolol) | 27 | Caucasian | Arg > Gly | Muszkat et al. (2013) |
Attenuation of exercise-induced HR and PRA increases (metoprolol) | 29 | Danish | Arg < Gly | Petersen et al. (2012) |
Attenuation of exercise-induced SBP and MAP response (atenolol) | 34 | American | Arg > Gly | Sofowora et al. (2003) |
HR, heart rate; MAP, mean arterial pressure; PRA, plasma renin activity; SBP, systolic blood pressure.