TABLE 2

Equivalent phases of the reproductive cycle in women and rats/mice

Women
FollicularPeriovulatoryLuteal
Estradiol secretion from ovaries as follicle developsRapid increase in estradiol that triggers luteinizing hormone surge that induces ovulationRelease of relatively high concentrations of both estradiol and progesterone from the corpus luteum
Rats/Mice
Metestrus/DiestrusProestrus/EstrusNo equivalent phase
Estradiol secretion from ovaries as follicle developsRapid increase in estradiol that triggers luteinizing hormone surge that induces progesterone release and ovulation