TABLE 1 

Wnts and cardiovascular development

GenePathwayRoleReference
WNT1β-catenin mediatedCardiac neural crest cell development and outflow tract developmentBrault et al. (2001)
WNT2Bnon-β-catenin mediatedInhibition of cardiac progenitor cellsWang et al. (2007)
WNT3Aβ-catenin mediatedMesoderm formationLiu et al. (1999)
Inhibition of cardiac progenitor cellsMarvin et al. (2001)
WNT5Anon-β-catenin mediatedCardiomyocyte differentiation and outflow tract septationSchleiffarth et al. (2007)
WNT7Anon-β-catenin mediatedConduction system developmentBond et al. (2003)
WNT9Bβ-catenin mediatedEpicardium development and coronary artery formationZamora et al. (2007)
WNT11non-β-catenin mediatedCardiomyocyte differentiationPandur et al. (2002)
Outflow tract septationZhou et al. (2007)
Conduction system developmentBond et al. (2003)