TABLE 4

Cellular and tissue expression profile of TAARs

Mammalian TAARSpeciesExpressionMethod
TAAR1Human,ad mouse,b,el ratj,mpVTA,e,k substantia nigra,k DRN,e,k amygdala,e,t rhinal cortices,e subiculum,e prefrontal cortex,np nucleus accumbens,o hypothalamus,e,t preoptic area,e spinal trigeminal nucleus,e medullary reticular nucleus,e nucleus of the solitary tract,e area postrema,e pancreatic β cells,a,f,g,l stomach (D cellsi),a,f,ik intestines (neuroendocrine cells,a,f enterochromaffin mucosal cellsd,s),a,d,f,j,k,s white adipose tissue,l spinal cord,m testes,j leukocytesb,c,hTAAR1-KO/lacZ KI mouse,e,f immunohistochemistry,a,c,o,p RT-PCR,b,gj,l,m,s RNA sequencing,i,k in situ hybridizationk,m
TAAR2Human,b,q,r mouse,b,h,q,s ratjOlfactory epithelium,q,r intestines,s testes,j leukocytesb,hRT-PCRb,hj,qs
TAAR3Mouse,q ratjOlfactory epithelium,q testesjRT-PCRq,j
TAAR4Mouse,l,q ratj,mOlfactory epithelium,l,q trachea,l spinal cord,m spleen,j testes,j musclejRT-PCR,j,l,m,q in situ hybridizationm
TAAR5Human,q,r mouse,b,h,q,t ratj,m,uOlfactory epithelium,q,r amygdala,t arcuate nucleus,t ventromedial hypothalamus,t spinal cord,m intestines,u testes,j leukocytesb,hRT-PCR,b,h,j,m,q,r,u in situ hybridizationt
TAAR6Human,k,q,r,v mouse,hj,l ratj,mOlfactory epithelium,l,q,r amygdala,k,v hippocampus,k,v basal ganglia,v frontal cortex,v substantia nigra,v spinal cord,m intestines,s testes,j kidney,k leukocyteshRT-PCRhl,qs,v
TAAR7Mousel,qOlfactory epitheliuml,qRT-PCRl,q
TAAR8Human,k,q,r mouse,c,h,j,l ratj,mOlfactory epithelium,q,r,t amygdala,k cerebellum,j cortex,j spinal cord,m islets of Langerhans,l intestines,j,l spleen,j,l testes,j heart,j lungs,j kidney,j,k leukocyteshRT-PCRc,h,jm,q,r
TAAR9Human,k,q,r,w mouse,h,i,l,s ratmOlfactory epithelium,q,r,t pituitary gland,w skeletal muscle,w spinal cord,m intestines,l,s spleen,l kidney,k leukocyteshRT-PCR,h,km,qs Northern blotw
  • KI, knock-in; RT-PCR, reverse transcription polymerase chain reaction.

  • a Raab et al. (2015).

  • b Nelson et al. (2007).

  • c Wasik et al. (2012).

  • d Kidd et al. (2008).

  • e Lindemann et al. (2008).

  • f Revel et al. (2013).

  • g Regard et al. (2007).

  • h Babusyte et al. (2013).

  • i Adriaenssens et al. (2015).

  • j Chiellini et al. (2012).

  • k Borowsky et al. (2001).

  • l Regard et al. (2008).

  • m Gozal et al. (2014).

  • n Espinoza et al. (2015b).

  • o Liu et al. (2018).

  • p Ferragud et al. (2017).

  • q Liberles and Buck (2006).

  • r Carnicelli et al. (2010).

  • s Ito et al. (2009).

  • t Dinter et al. (2015c).

  • u Kubo et al. (2015).

  • v Duan et al. (2004).

  • w Vanti et al. (2003).