Markers of somatostatin receptor ligand responsiveness in GH-secreting pituitary adenomas
Data adapted from Cuevas-Ramos et al. (2015).
| GH Granulation | Dense vs. Sparse Using CAM5.2 Cytokeratin Immunostaining |
|---|---|
| SST2, SST5 | Positive vs. negative expression |
| SST2:SST5 | High vs. low ratio of average SST2 to SST5 |
| SST5TMD4 | Low vs. high expression |
| AIP | Lack vs. presence of mutation or high vs. low protein expression |
| β-arrestin | Low vs. high score based on intensity and expression pattern |
| Filamin A | High vs. low score based on intensity and expression pattern |
| Gsp | Presence vs. absence of mutation |
| E-cadherin | High vs. low score based on intensity and expression pattern |