Initial and final model parameter estimates and their corresponding precision (CV%)
| Parameter | Initial Estimate | Final Estimate | CV% |
|---|---|---|---|
| R0 (mM) | 0.6 | 0.58 | 3 |
| kout (min−1) | 0.1 | 0.59 | 36 |
| ktol (min−1) | 0.07 | 0.058 | 25 |
| nH | 1 | 1.40 | 7 |
| ID50 (mmol) | 0.1 | 0.13 | 26 |
| K (min−1) | 0.2 | 0.22 | 13 |