Regular ArticleActivation of Ca2+ Release from Sarcoplasmic Reticulum Vesicles by 4-Alkylphenols
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Effects of alkylphenols on glycerophospholipids and cholesterol in liver and brain from female Atlantic cod (Gadus morhua)
2007, Comparative Biochemistry and Physiology - C Toxicology and PharmacologyAmino acid residues Gln<sup>4020</sup> and Lys<sup>4021</sup> of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol
2006, Journal of Biological ChemistryCitation Excerpt :These new data support a hypothesis in which the 4-CmC binding site most likely resides in close proximity to the lipid bilayer or even at the protein/lipid interface. This hypothesis is supported by studies on structural analogs of 4-CmC such as 4-alkyl phenols whose activity is directly proportional to the length of the 4-alkyl chain (21). These alkyl chains could anchor the compound to the membrane allowing the compound to diffuse to a binding site at the protein/lipid interface of RyR1.
Alkylphenol endocrine disrupters inhibit IP<inf>3</inf>-sensitive Ca <sup>2+</sup> channels
2003, Biochemical and Biophysical Research CommunicationsNonylphenol affects the granulation pattern of epidermal mucous cells in rainbow trout, Oncorhynchus mykiss
2000, Ecotoxicology and Environmental SafetyNonylphenol provokes a vesiculation of the Golgi apparatus in three fish epidermis cultures
2000, Ecotoxicology and Environmental SafetyThe ryanodine receptor agonist 4-chloro-3-ethylphenol blocks ORAI store-operated channels
2014, British Journal of Pharmacology
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