Regular ArticleComparative Mapping of the Grpr Locus on the X Chromosomes of Man and Mouse
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The role of bombesin and bombesin-related peptides in the short-term control of food intake
2013, Progress in Molecular Biology and Translational ScienceCitation Excerpt :Although the molecular weight of the human BB2 receptor is 60 kDa and the mouse is 82 kDa, the deglycosylated molecular weight for each of them is 43 kDa.134,162–165 The human BB2 receptor gene is localized on chromosome Xp22,166–168 and the gene has three exons spanning more than 27 kb with intron 1 and intron 2 being 23 and 1.6 kb,128,167 respectively. Expression of the BB2 receptor was studied in human, mouse, and monkey.18,124,128,135,136
The insulin response to gastric glucose is reduced in PAC1 and GRP receptor gene deleted mice
2006, Nutrition, Metabolism and Cardiovascular DiseasesCitation Excerpt :Heterozygous mice were backcrossed for at least 10 generations with inbred 129T mice; homozygous crosses were then set up to yield homozygous mutations and wild type mice. For generation of GRPR deficient mice, male C57BL/6J mice homizygous for the GRP receptor gene (which is located on chromosome X [14]), were generated by homologous recombination in embryonic stem cells as previously described [15]. The mice and their respective wild types were fed a standard pellet diet and tap water ad libitum.
Genetic mapping of the mouse genome
1998, Methods: A Companion to Methods in Enzymology