Regular ArticleThe Elimination Half-Life of Urinary Cotinine in Children of Tobacco-Smoking Mothers
References (0)
Cited by (46)
Urinary cotinine and exposure to passive smoke in children and adolescents in Germany – Human biomonitoring results of the German Environmental Survey 2014–2017 (GerES V)
2023, Environmental ResearchCitation Excerpt :As part of the study, an interview-guided standardised questionnaire was conducted and the urine cotinine levels of 2260 children and adolescents from all over Germany were examined. Cotinine is the main metabolite of nicotine and is considered a specific and valid urinary biomarker for the determination of passive smoke exposure within the last 20–40 h (Benowitz, 1996; Leong et al., 1998; U.S. Environmental Protection Agency, 1992). In combination with information on exposure-relevant behaviour, the GerES V data provide important references on the passive smoke exposure of children and adolescents in Germany.
Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates
2020, Toxicology and Applied PharmacologyEffects of Smoking Exposure in Infants on Gastroesophageal Reflux as a Function of the Sleep–Wakefulness State
2018, Journal of PediatricsCitation Excerpt :In infants from nonsmoking mothers, paternal smoking was the most significantly related determinant of measurable levels of urinary cotinine. In neonates, Etzel et al found an averaged cotinine half-life of 68 hours (range: 37-160 hours), whereas Leong et al found a median half-life of 28.3 hours (range: 6-259 hours) in infants.60,61 In the present study, our assay's limit of detection (1 ng/mL) enabled us to measure any exposure to nicotine.
Gender differences in cadmium and cotinine levels in prepubertal children
2015, Environmental ResearchMedico-social aspects of patients with bronchial asthma
2015, KontaktCitation Excerpt :Nicotine metabolite cotinine is a bio-marker of nicotine changes. It is half-life for breaking down was longer (17–24 h) than nicotine (2–3 h) [73,74]. Cotinine (nicotine metabolite) can be detected in urine, saliva, blood and hair [75].
Perinatal nicotine/smoking exposure and carotid chemoreceptors during development
2013, Respiratory Physiology and NeurobiologyCitation Excerpt :Such levels are essential to show that the results are valid, i.e., that the control and smoke-exposed groups differed. Cotinine levels have been reported in urine (Lewis and Bosque, 1995; Parslow et al., 2004; Poole et al., 2000), hair (Sovik et al., 1999) or saliva (Campbell et al., 2001). However, some caution must be taken in interpreting these results since cotinine in body fluids does not provide a detailed history of tobacco smoke exposure throughout pregnancy, particularly as regards to its short half-life.
- f1
Author for correspondence.