Summary
Methanol extracts of the skin of the African amphibian Kassina senegalensis contain a dodecapeptide, kassinin, belonging to the family of tachykinins or physalaemin-like peptides. Kassinin, like all other natural tachykinins, possesses the characteristic C-terminal tripeptide Gly-Leu-Met-NH2 and a phenylalanine residue in position 5 from the C-terminus. However, the amino acid sequence in the N-moiety of the molecule differs sharply from that of the other tachykinins.
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Supported in part by grants from the Consiglio Nazionale delle Ricerche, Roma.
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Anastasi, A., Montecucchi, P., Erspamer, V. et al. Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. Experientia 33, 857–858 (1977). https://doi.org/10.1007/BF01951242
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DOI: https://doi.org/10.1007/BF01951242