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The identification of dehydroretinol (vitamin A2) in human skin

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Summary

Vitamin A2 has for the first time been identified in a human tissue and, in contrast to vitamin A1, its concentration in the epidermis is markedly increased in a hyperkeratotic condition (Psoriasis vulgaris).

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Acknowledgments. The valuable discussions with Prof. I. Björk, Drs A. de Belder, C. Lindberg and J.B. Lee are gratefully acknowledged. Purified retinoids were generously supplied by F. Hoffmann-LaRoche Co. AG, Basle. This project was supported by grants from the Swedish Medical Research Council (B78-03x-05174), the Welander Foundation and the Tore Nilsson Fund.

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Vahlquist, A. The identification of dehydroretinol (vitamin A2) in human skin. Experientia 36, 317–318 (1980). https://doi.org/10.1007/BF01952299

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