Summary
Rats treated with 50 or 300 mg/kg capsaicin were less tolerant of a warm environment than controls. However, preoptic thermoregulatory impairment, as shown by a decreased vasodilatation on preoptic heating, was not found for the lower dose, suggesting a deficiency in extrahypothalamic thermoreceptive structures.
References
Jancso-Gabor, A., Szolcsanyi, J., and Jancso, N., J. Physiol., Lond.206 (1970) 495.
Szolcsanyi, J., and Jancso-Gabor, A., in: Temperature regulation and drug action, p. 331. Eds P. Lomax, E. Schönbaum and J.J. Jacob. Karger, Basel 1975.
Szolcsanyi, J., and Jancso-Gabor, A., in: The pharmacology of thermoregulation, p. 395. Eds P. Lomax and E. Schönbaum. Karger, Basel 1973.
Obal, Jr, F., Benedek, G., Jancso-Gabor, A., and Obal, F., Pflügers Arch.382 (1979) 249.
Obal, Jr, F., Benedek, G., Jancso-Gabor, A., and Obal, F., Pflügers Arch.387 (1980) 183.
Cabanac, M., Cormareche-Leydier, M., and Poirier, L.J., Pflügers Arch.366 (1976) 217.
Hori, T., in: Thermoregulatory mechanisms and their therapeutic implications, p. 214. Eds B. Cox, P. Lomax, A.S. Milton and E. Schönbaum. Karger, Basel 1980.
Jancso-Gabor, A., Szolcsanyi, J., and Jancso, N., J. Physiol., Lond.208 (1970) 249.
Szolcsanyi, J., Joo, F., and Jancso-Gabor, A., Nature, Lond.229 (1971) 116.
Nakayama, T., Suzuki, M., Ishikawa, Y., and Nishio, A., Neurosci. Lett.7 (1978) 151.
Hori, T., Pflügers Arch.389 (1981) 297.
Cormareche-Leydier, M., Pflügers Arch.389 (1980) 171.
Obal, Jr, F., Hajos, M., Benedek, G., Obal, F., and Jancso-Gaor, A., Physiol. Behav.27 (1981) 977.
Szolcsanyi, J., in: Contributions to thermal physiology, p. 61. Eds Z. Szelenyi and M. Szekely. Pergamon Press-Akademiai Kiado, Oxford-Budapest 1981.
Meeter, E., in: The pharmacology of thermoregulation, p. 492. Eds E. Schönbaum and P. Lomax. Karger, Basel 1973.
Jancso, G., Kiraly, E., and Jancso-Gabor, A., Nature, Lond.270 (1977) 741.
Jancso, G., and Kiraly, E., J. comp. Neurol.190 (1980) 781.
Jancso, G., and Jancso-Gabor, A., Naunyn-Schmiedebergs Arch. Pharmak.311 (1980) 285.
Jancso, N., Jancso-Gabor, A., and Szolcsanyi, J., Br. J. Pharmac. Chemother.31 (1967) 138.
Nakayama, T., Ishikawa, Y., and Tsurutani, T., Pflügers Arch.380 (1979) 59.
Ishikawa, Y., Nakayama, T., and Tsurutani, T., in: Contributions to thermal physiology, p. 105 Eds Z. Szelenyi and M. Szekely. Pergamon Press-Akdemiai Kiado, Oxford-Budapest 1981.
Hori, T., in: Contributions to thermal physiology, p. 53. Eds Z. Szelenyi and M. Szekely. Pergamon Press-Akademiai Kiado, Oxford-Budapest 1981.
Hori, T., and Tsuzuki, S., Pflügers Arch.390 (1981) 219.
Nagy, J.I., Vincent, S.S., Staines, W.M.A., Fibiger, H.C., Reisine, T.D., and Yamamura, H.I., Brain Res.186 (1980) 435.
Kessler, J.A., and Black, I.B., Proc. natl. Acad. Sci. USA78 (1981) 4644.
Foster, R.W., and Ramage, A.G., Neuropharmacology20 (1981) 191.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Obal, F., Jancso, G., Jancso-Gabor, A. et al. Vasodilatation on preoptic heating in capsaicin-treated rats. Experientia 39, 221–223 (1983). https://doi.org/10.1007/BF01958912
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01958912