Suppression of ethanol self-administration in alcoholics by contingent time-out from social interactions
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Cited by (26)
Animal models of social contact and drug self-administration
2015, Pharmacology Biochemistry and BehaviorCitation Excerpt :Similarly, subjects in another study reported higher ratings of intoxication when tested with a social partner who also drank alcohol than when tested with a social partner who did not drink alcohol (Kirkpatrick and de Wit, 2013). Consistent with increased alcohol consumption and subject-rated effects in social contexts, Griffiths and colleagues (1974) reported that placing time-outs from social interaction contingent on alcohol choice was sufficient to suppress the choice to drink alcohol. Taken together, these findings reveal that the presence of a peer and his or her drinking behavior critically influence the subjective and reinforcing effects of alcohol.
Cocaine abuse versus cocaine dependence: Cocaine self-administration and pharmacodynamic response in the human laboratory
2010, Drug and Alcohol DependenceCitation Excerpt :To examine differences between cocaine abusers with and without cocaine dependence with respect to their response to cocaine, drug-directed behaviors, or factors that may confer risk or resiliency to drug-taking and relapse in the laboratory, this study capitalized upon paradigms designed to assess drug-seeking behavior that have been developed and widely explored with non-human and, to a lesser extent, human subjects. Human self-administration studies have examined the influence of pharmacological factors (e.g., Fischman et al., 1990; Foltin and Fischman, 1994) and environmental factors (Griffiths et al., 1974; Silverman et al., 1994) on drug self-administration. To our knowledge, this paradigm has not been applied to study individual differences in the vulnerability to cocaine dependence, differences between groups who vary in their drug use characteristics, or the influence of environmental and pharmacological factors on cocaine-seeking behavior in dependent and non-dependent drug users.
Incorporating the assessment of abuse liability into the drug discovery and development process
2003, Drug and Alcohol DependenceSocial drinking in a simulated tavern: An experimental analysis
1984, Drug and Alcohol DependenceEffects of response-contingent clock stimuli on behavior maintained by intravenous codeine in the rhesus monkey
1979, Pharmacology, Biochemistry and Behavior