Biochemical and Biophysical Research Communications
Intracellular histamine and liver regeneration: High affinity binding of histamine to chromatin, low affinity binding to matrix, and depletion of a nuclear storage pool following partial hepatectomy
References (24)
- et al.
Biochem. Biophys. Res. Commun
(1992) - et al.
Biochem. Pharmacol
(1990) - et al.
Blood
(1990) Methods in Cell Biol
(1976)- et al.
J. Biol. Chem
(1972) - et al.
J. Chromat
(1985) - et al.
Biochem. Pharmacol
(1967) - et al.
Biochem. Pharmacol
(1988) - et al.
Science
(1989) - et al.
Cancer Res
(1987)
J. Natl. Cancer Inst
Agents and Actions
Cited by (31)
The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers
2018, Biochemical PharmacologyCitation Excerpt :Histamine was the only non-lipidic compound ever described as an AEBS ligand, and the AEBS was considered as an intracellular binding site for histamine (HIC) for a while [47,48]. Histamine is involved in pleiotropic physiological functions such as neurotransmission, inflammation and gastric acid secretion [49] and was proposed to play a role in cell proliferation through the AEBS-HIC [47,50–53]. Tam and selective AEBS ligands were considered as antagonists of histamine on HIC [46,54,55] before the molecular identification of the AEBS was made.
Improving the efficacy of hormone therapy in breast cancer: The role of cholesterol metabolism in SERM-mediated autophagy, cell differentiation and death
2017, Biochemical PharmacologyCitation Excerpt :Other DPM compounds have also been chemically synthesized and among them structure-affinity studies have shown that PBPE (Fig. 1E) is one of the highest affinity ligands for the AEBS [49]. DPPE and PBPE have been the most studied selective AEBS ligands [15,27,55–64], and when DPPE was brought to the clinic under the trade name of tesmilifene it showed some efficacy in cancer treatment [61,65–69]. DPPE and PBPE were shown to be selective for the AEBS with no impact on ER [49], ACAT [48], PKC [70,71] or calmodulin [63,72], evidencing that DPM compounds are useful tools for defining the importance of the AEBS in the anticancer pharmacology of SERMs.
FT-Raman and QM/MM study of the interaction between histamine and DNA
2006, Chemical PhysicsHistamine Influences the Blood-Spinal Cord and Brain Barriers Following Injuries to the Central Nervous System
2004, Blood-Spinal Cord and Brain Barriers in Health and Disease