Biochemical and Biophysical Research Communications
Volume 188, Issue 3, 16 November 1992, Pages 1030-1039
[125I]EXP985: A highly potent and specific nonpeptide radioligand antagonist for the AT1 angiotensin receptor
References (26)
- et al.
Biochem. Biophys. Res. Commun
(1989) - et al.
Biochem. Biophys. Res. Commun
(1989) - et al.
Biochem. Biophys. Res. Commun
(1990) - et al.
Biochem. Biophys. Res. Commun
(1991) - et al.
Eur. J. Pharmacol
(1988) - et al.
Biochem. Biophys. Res. Commun
(1991) - et al.
Trends Pharmacol. Sci
(1991) - et al.
FEBS Left
(1992)
Adv. Exp. Med
(1980)
Pharmacotherapy
(1989)
Hypertension
(1991)
Cited by (16)
Sarcosine<sup>1</sup>,glycine<sup>8</sup> angiotensin II is an AT <inf>1</inf> angiotensin II receptor subtype selective antagonist
2003, Regulatory PeptidesCitation Excerpt :However, 3H-losartan has considerable non-AT1 receptor binding sites [10]. An attempt was made to radioiodinate the losartan analog, Exp985 [11], but this radioligand abundantly bound to albumin, obscuring AT1 receptor binding. Another nonpeptide AT1 receptor antagonist SK&F 108566 (eprosartan) has been radiolabeled with 3H and used to identify AT1 receptors [12].
Candesartan (CV-11974) dissociates slowly from the angiotensin AT<inf>1</inf> receptor
1997, European Journal of PharmacologyBinding of valsartan to mammalian angiotensin AT<inf>1</inf> receptors
1995, Regulatory Peptides[<sup>3</sup>H]A-81988, a potent, selective, competitive antagonist radioligand for angiotensin AT<inf>1</inf> receptors
1994, European Journal of Pharmacology: Molecular Pharmacology
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