Elsevier

Biological Psychiatry

Volume 29, Issue 1, 1 January 1991, Pages 15-22
Biological Psychiatry

Phenylethylaminergic mechanisms in attention-deficit disorder

https://doi.org/10.1016/0006-3223(91)90207-3Get rights and content

Abstract

Urinary excretion (24-hr) of β-phenylethylamine (PEA), phenylacetic acid (PAA), phenylalanine (Phe), and p-tyrosine (Tyr), and plasma levels of PAA, Phe, and Tyr were examined in 18 normal children and 26 children diagnosed as having attention-deficit hyperactivity disorder (ADHD). The results indicated that urinary excretion (expressed per g of creatinine) of free and total PEA was significantly lower in the ADHD patients, and plasma levels of Phe and Tyr were also decreased in the ADHD subjects compared with the normal controls.

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