Elsevier

Brain Research

Volume 116, Issue 2, 5 November 1976, Pages 299-305
Brain Research

Regional distribution of substance P in the brain of the rat

https://doi.org/10.1016/0006-8993(76)90907-0Get rights and content

Abstract

Using a sensitive radioimmunoassay we have studied the regional distribution of substance P. The level of substance P is higher in the mesencephalon, hypothalamus and preoptic area than in other regions of the brain. Substance P is found in especially high concentrations in the reticular part of the substantia nigra and the interpeduncular nucleus. It is present in large amounts in several septal, preoptic and hypothalamic nuclei as well.

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