A reinvestigation of the fatty acid content of bovine, rat and frog retinal rod outer segments
References (33)
- et al.
Lipids of ocular tissues—X. Lipid composition of subcellular fractions of bovine retina
Vision Res.
(1975) - et al.
Lipids of ocular tissues—IX. The phospholipids of frog photoreceptor membranes
Vision Res.
(1974) - et al.
Lipids of ocular tissues—VII. Positional distribution of the fatty acids in the phospholipids of bovine retina rod outer segments
Arch. Biochem. Biophys.
(1971) A rapid and sensitive method for the quantitation of microgram quantities or protein utilizing the principle of protein-dye binding
Analyt. Biochem.
(1976)Vertebrate rod outer segment membranes
Biochim. Biophys. Acta
(1973)- et al.
Oxidative damage of retinal rod outer segment membranes and the role of vitamin E
Biochim. Biophys. Acta
(1976) - et al.
Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol
J. Lipid Res.
(1964) - et al.
Fatty acid composition of bovine rod outer segments and rhodopsin
Biochim. Biophys. Acta
(1970) - et al.
A rapid method for the purification of rod outer segment disk membranes
Vision Res.
(1974) - et al.
Depletion of docosahexaenoic acid in retinal lipids of rats fed a linolenic acid-deficient linoleate-containing diet
Biochim. Biophys. Acta
(1977)
Phospholipids of bovine rod outer segments
Biochemistry
Lipids of ocular tissues—VIII. The effects of essentia fatty acid deficiency on the phospholipids of the photoreceptor membranes of rat retina
Arch. Biochem. Biophys.
Phosphorus assay in column chromatography
J. Biol. Chem.
Light-sensitive swelling of isolated frog rod outer segments as an in vitro assay for visual transduction and dark adaptation
J. Gen. Phys.
Spectrofluorometric determination of tocopherols
Arch. Biochem. Biophys.
Cited by (208)
Impacts of high fat diet on ocular outcomes in rodent models of visual disease
2021, Experimental Eye ResearchThe role of reactive oxygen species in the pathogenesis and treatment of retinal diseases
2020, Experimental Eye ResearchCitation Excerpt :ROS are not only generated in higher amounts in the retina, but the potential for oxidative damage amongst retinal cells is also increased. Photoreceptors are rich in polyunsaturated fatty acids, particularly docosahexaenoic acid, which is extremely susceptible to lipid peroxidation (Stone et al., 1979). In order to overcome this, the retina possesses multiple ROS scavengers (Kortuem et al., 2000) and continually phagocytoses the photoreceptor outer segment to minimise oxidative damage (Miceli et al., 1994).
Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration
2019, BiochimieCitation Excerpt :Docosahexaenoic acid (DHA) is a major representative of long-chain (LC) polyunsaturated fatty acids (PUFAs). This member of omega-3 LC-PUFAs is present in high quantities in POS [8]. The relative amount of DHA in POS is the highest of any tissues when compared to the amount of total fatty acids levels.
Evaluation of in-situ fatty acid extraction protocols for the analysis of staphylococcal cell membrane associated fatty acids by gas chromatography
2018, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life SciencesCitation Excerpt :This inherently gives the acidic transesterification procedure an advantage in most biological scenarios. The extraction of certain key polyunsaturated fatty acids can be influenced by the availability of anti-oxidant protection in the matrix along with the condition of the pathway [56]. BHT is often used with biological material as it is proposed to provide protection to PUFAs through the scavenging of free radicals which in turn prevents the free radicals from stripping protons from the methylene groups in PUFA molecules [57].
Molecular basis for photoreceptor outer segment architecture
2016, Progress in Retinal and Eye ResearchCitation Excerpt :Finally, a recent report suggests that photoreceptors may possess a means to transport proteins from the OS to the cell body (Datta et al., 2015); additional studies would be required to assess the potential impact of this retrograde pathway on lipid trafficking. The ease with which rod OSs can be purified has facilitated extensive characterizations of their lipid composition (Anderson and Maude, 1970; Aveldano and Bazan, 1983; Fliesler and Anderson, 1983; Stone et al., 1979). In contrast, the low abundance and less accessible histological position of cone OSs have prevented rigorous assessments to date.
The stability of blood fatty acids during storage and potential mechanisms of degradation: A review
2016, Prostaglandins Leukotrienes and Essential Fatty Acids