Nitrendipine-induced gingival hyperplasia: First case report

https://doi.org/10.1016/0030-4220(90)90406-IGet rights and content

Abstract

Drug-induced gingival hyperplasia is well documented within the literature. It has been associated with phenytoin, cyclosporine, and calcium channel blocking agents. Nitrendipine is an experimental calcium channel blocking agent that also appears to cause the side effect of drug-induced gingival hyperplasia. The clinical and histologic presentation of this side effect and possible biochemical mechanisms of pathogenesis are discussed.

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    a

    Associate Professor, Department of Oral Diagnostic Sciences, UTHSCH, Dental Branch.

    b

    Clinical Instructor, Department of Oral Pathology, Georgetown University.

    c

    Professor and Chairman, Department of Oral Pathology, Georgetown University.

    d

    Professor and Chairman, Department of Oral Diagnosis, Georgetown University.

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