Effects of [Des-Tyr1]-γ-endorphin and α-endorphin on substantia nigra self-stimulation
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Cited by (45)
kappa-Opioid receptor signaling and brain reward function
2009, Brain Research ReviewsCitation Excerpt :There is some evidence to suggest that α-endorphin and γ-endorphin have opposite effects on brain reward function. Dorsa et al. (1979) demonstrated that α-endorphin potentiated self-stimulation of the ventral tegmental area/substantia nigra region and (Des-Tyr)-γ-endorphin inhibited self-stimulation in this region. ( Des-Tyr)-γ-endorphin is similar to γ-endorphin with the exception that the tyrosine at position one is removed.
Des-tyrosine-γ-endorphin effects on morphine analgesia in mice
1993, General PharmacologyThe neuropeptide, Org 5878 (desenkephalin-γ-endorphin, DE γ E), affects local cerebral glucose utilization in freely moving rats
1989, European Journal of PharmacologyThe neuropeptide concept
1987, Progress in Brain ResearchAnimal and clinical research on neuropeptides and schizophrenia
1987, Progress in Brain Research
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Recipient of an International Brain Research Organization (UNESCO) travel grant. Present address: Department of Physiology, Stanford University, Stanford, CA.
Copyright © 1979 Published by Elsevier Inc.