Cell
Volume 32, Issue 4, April 1983, Pages 1026-1028
MinireviewPerturbation of vesicular traffic with the carboxylic ionophore monensin
References (0)
Cited by (683)
A multiaspect study on transcytosis mechanism of sorafenib nanogranules engineered by high-gravity antisolvent precipitation
2020, Journal of Controlled ReleaseInvestigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes
2017, Advanced Drug Delivery ReviewsThe kringle-like domain facilitates post-endoplasmic reticulum changes to premelanosome protein (PMEL) oligomerization and disulfide bond configuration and promotes amyloid formation
2016, Journal of Biological ChemistryCitation Excerpt :To verify band identity and to probe for potential precursor-product relationships, MNT-1 cells were treated with small molecule inhibitors of trafficking and processing steps. Detergent-soluble lysates were then analyzed by non-reducing SDS-PAGE and immunoblotted with HMB45 or αPMEL-C. Treatment of MNT-1 cells with monensin, an inhibitor of intra-Golgi transport (53), led to the accumulation of p250 and higher Mr oligomers as well as the concomitant depletion of p160 (Fig. 6, A and B, lane 2). This supports the conclusion that p250 forms during ER exit or in the early Golgi and that p160 forms in the trans-Golgi network or later.
Repurposing Polyether Ionophores as a New-Class of Anti-SARS-Cov-2 Agents as Adjunct Therapy
2023, Current Microbiology
Copyright © 1983