Cell
Volume 50, Issue 7, 25 September 1987, Pages 1001-1010
ArticleThe yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
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2008, International Review of Cell and Molecular BiologyCitation Excerpt :The secondary structure predicted for amoeba Gγ has 2.5 helices, like it was in transducin Gγ‐subunit of vertebrates. Two types of Gα‐subunits—Gpa1 and Gpa2—that participate in transduction of signals generated by pheromones (Gpa1) and sugars (Gpa2) are found in the genomes of yeasts S. cerevisiae and S. pombe (Dietzel and Kurjan, 1987; Isshiki et al., 1992; Miyajima et al., 1987; Nakafuku et al., 1987, 1988; Obara et al., 1991; Slessareva and Dohlman, 2006). Both types of Gα‐subunits have a comparatively high homology of the primary structure to Gα in other unicellular organisms and in higher eukaryotes.
Copyright © 1987