Cell
ArticleAll-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs
References (89)
- et al.
Phorbol esterinducible genes contain a common cis element recognized by a TPA-modulated trans-acting enhancer
Cell
(1987) - et al.
Molecular cloning of two human cellular retinoic acid-binding proteins CRABP
J. Biol. Chem.
(1991) - et al.
Purification and partial characterization of a novel binding protein for retinoic acid from neonatal rat
J. Biol. Chem.
(1988) CRABP and the teratogenic effects of retinoids
Trends Genet
(1991)Gene regulation by steroid hormones
Cell
(1989)- et al.
Terminal differentiation of human promyelocytic leukemia cells in primary culture in response to retinoic acids
Blood
(1981) Retinoids, homeobox genes, and limb morphogenesis
Neuron
(1989)- et al.
A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable
Cell
(1988) - et al.
The cellular retinol binding protein II gene: sequence analysis of the rat gene, chromosomal localization in mice and humans, and documentation of its close linkage to the cellular retinol binding protein gene
J. Biol. Chem.
(1987) - et al.
Cellular retinoic acid-binding protein type 2 mRNA is overexpressed in human psoriatic skin as shown by in situ hybridization
Biochem. Biophys. Res. Commun.
(1991)
Differential regulation of retinoic acid receptors and binding proteins in human skin
J. Invest. Dermatol.
Nuclear receptors enhance our understanding of transcription regulation
Trends Genet.
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
Cell
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
Gene
Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP
Cell
Ear3/COUPTF binds most tightly to a response element with tandem repeat separated by one nucleotide
Biochem. Biophys. Res. Commun.
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
Cell
Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells
Biochim. Biophys. Acta
A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR
Cell
Retinoids in vertebrate limb development
Dev. Biol.
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 inhibited by SV40 T antigen
Cell
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors
Cell
Retinoic acid, a developmental signalling molecule
Trends Neurosci.
Retinoids, homeoboxes, and growth factors: toward molecular models for limb development
Cell
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
Cell
RXRβ: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
Cell
Vitamin A metabolism: new perspectives on absorption, transport and storage
Physiol. Rev.
Multiple retinoid-responsive receptors in a single cell: families of retinoid “X” receptors and retinoic acid receptors in the Xenopus egg
Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells
J. Cell Biol.
Purification and biochemical characterization of the promoter-specific transcription factor Sp1
Science
Reading the retinoid signals
Nature
RXRα, a promiscuous partner of retinoic acid and thyroid hormone receptors
EMBO J.
The family of retinoic acid nuclear receptors
Cellular retinoic acid- and retinol-binding proteins
Expression of cloned genes in new environment: promoter sequences of eukaryotic protein-coding genes
Science
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia
FASEB J.
Identification of a retinoic acid responsive element in the retinoic acid receptor β gene
Nature
Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse
Nature
Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis
Development
Retinoic acid enhancer colony-stimulating factor induces clonal growth of normal human myeloid progenitor cells in vitro
Exp. Cell Res.
Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis
Mol. Cell. Biol.
The steroid and thyroid hormone receptor superfamily
Science
Molecular cloning of cDNA encoding a second cellular retinoic acid-binding protein
A versatile in vivo and in vitro eukaryotic expression vector for protein engineering
Nucl. Acids Res.
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2023, Acta Pharmaceutica Sinica BCARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation
2018, Journal of Molecular BiologyCitation Excerpt :We treated J1 WT, shCtl, and CARM1 KD cells with vehicle (0.1% EtOH) or 1 μM RA for 48 h and measured the transcript levels of a number of well-characterized RA-inducible genes, including CRABP2, Cyp26b1, HoxA1, NR2F1, and NR2F2; these genes play key roles during RA-induced differentiation of ESCs [1,2]. For example, CRABP2 and Cyp26b1 are involved in RA metabolism and transport [23–25]. CRABP2 is responsible for transporting RA from the cytoplasm into the nucleus [25].
Mechanisms of retinoic acid signaling during cardiogenesis
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2015, Molecular Aspects of MedicineVitamin a deficiency causes hyperglycemia and loss of pancreatic β-cell mass
2015, Journal of Biological ChemistryCitation Excerpt :Collectively, these data demonstrate that VA deprivation results in elevations in random glucose blood levels, impaired glucose-stimulated insulin secretion, and decreased pancreatic insulin content, but no alterations in peripheral insulin sensitivity. The biologically active form of VA, all-trans-RA, can increase the transcript levels of some VA metabolizing proteins, such as Cyp26a1, and RA binding proteins, such as Crabp2 and RARβ2 (18–20). Thus, the relative mRNA levels of these and other RA-regulated genes can serve as a readout of the retinoid status and responsiveness of tissue.