Special feature
Rodbell and Gilman win 1994 Nobel Prize for Physiology and Medicine

https://doi.org/10.1016/0165-6147(94)90053-1Get rights and content

First page preview

First page preview
Click to open first page preview

References (22)

  • E.W. Sutherland et al.

    J. Biol. Chem.

    (1962)
  • L. Birnbaumer et al.

    J. Biol. Chem.

    (1969)
  • M. Rodbell et al.

    J. Biol. Chem.

    (1971)
  • M. Rodbell et al.

    J. Biol. Chem.

    (1971)
  • D. Cassel et al.

    Biochim. Biophys. Acta

    (1976)
  • D.M.F. Cooper et al.

    J. Biol. Chem.

    (1979)
  • E.M. Ross et al.

    J. Biol. Chem.

    (1977)
  • B.R. Conklin et al.

    Cell

    (1993)
  • J.R. Hepler et al.

    Trends Biochem. Sci.

    (1992)
  • J.P. Changeux et al.
  • R.J. Lefkowitz et al.
  • Cited by (7)

    • Advances in the molecular level understanding of G-protein coupled receptor

      2023, Progress in Molecular Biology and Translational Science
      Citation Excerpt :

      Although, many GPCRs display basal activity, complete activation of GPCRs is mediated by heteromeric G proteins, G-protein coupled receptor kinase (GRK)-mediated phosphorylation and arrestin coupling.1,2 Historically, research work by several pioneers such as Rodbell and Gilman led to the discovery of heteromeric G proteins, followed by discoveries of GRKs, arrestins, rhodopsin kinase and β-adrenergic receptor kinase (βARK).3,4 Recently, advanced molecular techniques including NMR, single molecule fluorescence, X-ray crystallography and cryo electron microscopy have unfolded fascinating molecular details of more than 350 GPCRs5–7 and this family of proteins display one of the most important pharmacological potential and therapeutic target.8

    • Role of soluble adenylyl cyclase in the heart

      2012, American Journal of Physiology - Heart and Circulatory Physiology
    View all citing articles on Scopus
    View full text