In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat
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Cited by (37)
Neurotensin, schizophrenia, and antipsychotic drug action
2003, International Review of NeurobiologyThe role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs
2001, Biological PsychiatryCitation Excerpt :The neuromodulatory effects of NT are specific for NT receptor activation, as these effects are not mimicked by either glutamate or choleycystokinin, both neurotransmitters that also increase DA cell firing (Shi and Bunney 1991b). Dopamine neurons in the VTA and SN display different thresholds for NT-induced depolarization (Seutin et al 1989; Shi and Bunney 1990) and depolarization inactivation (Shi and Bunney 1991a), with NT having a greater effect in the VTA than in the SN (Myers and Lee 1983; Pinnock and Woodruff 1994; Seutin et al 1989). This effect is similar to atypical antipsychotic drugs that exert relatively selective effects on the VTA.
G<inf>αq/11</inf> mediates neurotensin excitation of substantia nigra dopaminergic neurons
1996, Molecular Brain Research
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