Histamine hyperpolarizes hippocampal neurones in vitro
References (9)
- et al.
A simple perfusion chamber for the study of nervous tissue slices in vitro
J. neurosci. Meth.
(1979) - et al.
Central actions of histamine: microelectrophoretic studies
Brain Res.
(1977) Histamine produces a Ca2+-sensitive depolarization of hippocampal pyramidal cells in vitro
Neurosci. Lett.
(1980)- et al.
The ionic mechanisms concerned in generating the i.p.s.ps of hippocampal pyramidal cells
Cited by (29)
Ventral hippocampal histamine increases the frequency of evoked theta rhythm but produces anxiolytic-like effects in the elevated plus maze
2016, NeuropharmacologyCitation Excerpt :The neuroanatomically distinct effects of histamine on both behavior and theta properties highlight the pharmacological complexity and functional heterogeneity of histamine as a neurotransmitter in the hippocampus. Within the hippocampus, it has been observed that histamine injected into different cell layers can induce both depolarization and hyperpolarization of neuronal membrane potentials (Haas, 1981; Segal, 1981). With regards to this, it has been suggested that the inhibitory and behaviorally regulating actions of histamine may be localized to the ventral hippocampus.
Histamine Influences the Blood-Spinal Cord and Brain Barriers Following Injuries to the Central Nervous System
2004, Blood-Spinal Cord and Brain Barriers in Health and DiseaseExcitatory effects of histamine on cerebellar interpositus nuclear cells of rats through H<inf>2</inf> receptors in vitro
2002, Brain ResearchCitation Excerpt :However, this concept has been challenged recently [2]. Although activation of histamine H2 receptors in some brain areas cause a depression in neuronal firing [9,19], very little is known about the mechanism of the inhibition compared to the good understanding of the excitatory effect of histamine on the neuronal activity via the histamine H2 receptor-linked mechanisms [2]. At least, in the cerebellum the possibility that the histamine-induced inhibition was caused by an indirect presynaptic action of GABAergic neurons cannot be ruled out in our previous studies [22,34].
The physiology of brain histamine
2001, Progress in NeurobiologyCentral histaminergic system and cognition
2000, Neuroscience and Biobehavioral ReviewsHistamine excites rat cerebellar Purkinje cells via H<inf>2</inf> receptors in vitro
2000, Neuroscience Research