Elsevier

Neuroscience Letters

Volume 29, Issue 1, 17 March 1982, Pages 83-88
Neuroscience Letters

Responses of single nerve fibres to capsaicin applied to the skin

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Abstract

The responses of sensory nerve fibres to capsaicin solution topically applied to their cutaneous receptive fields were studied using the rat saphenous nerve. The polymodal nociceptors responded to capsaicin with discharge and subsequent densensitization to chemical, mechanical and thermal stimuli. Other types of C fibres, and Aβ and Aδ fibres, showed no response to capsaicin.

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