Elsevier

Neuroscience Letters

Volume 168, Issues 1–2, 28 February 1994, Pages 97-100
Neuroscience Letters

In situ hybridization study of μ- and κ-opioid receptor mRNAs in the rat spinal cord and dorsal root ganglia

https://doi.org/10.1016/0304-3940(94)90425-1Get rights and content

Abstract

Distributions of μ- and κ-opioid receptor mRNAs in the lumbar spinal cord and dorsal root ganglia of the adult rat were examined using the in situ hybridization technique. In the lumbar spinal cord, μ-opioid receptor mRNA was expressed intensely in laminae I, II and VIII. On the other hand, κ-opioid receptor mRNA was expressed intensely in laminae I and II, and moderately throughout laminae III-VIII. In the dorsal root ganglia, μ-opioid receptor mRNA was intensely expressed and κ-opioid receptor mRNA was expressed in a smaller number of cells than μ-opioid receptor mRNA.

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