Elsevier

Journal of Chemical Neuroanatomy

Volume 5, Issue 2, March–April 1992, Pages 169-180
Journal of Chemical Neuroanatomy

Diazepam binding inhibitor processing in the rhesus monkey brain: An immunocytochemical study

https://doi.org/10.1016/0891-0618(92)90042-OGet rights and content

Abstract

Immunocytochemical methods were used to study the regional and cellular distribution of diazepam binding inhibitor (DBI)-, ODN (DBI 33–50)- and TTN (DBI 17–50)-like immunoreactivity (LI) in monkey brain. DBI-, ODN- and TTN-LI were found to have similar regional but different cellular distributions. The most intense staining was detected in limbic structures, especially the amygdala. The most notable staining discrepancy was the weak-to-moderate uniform DBI-LI and the very high patchy ODN-LI and TTN-LI in the ventral striatum. At the cellular level, DBI-LI was preferentially localized in glia-like cells, whereas ODN-LI and TTN-LI were mainly found in neurons.

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