Original contributionEndogenous ubiquinol prevents protein modification accompanying lipid peroxidation in beef heart submitochondrial particles
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Cited by (104)
Understanding Ubiquinone
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2014, Biochimica et Biophysica Acta - BioenergeticsIn vivo changes in plasma coenzyme Q10, carotenoid, tocopherol, and retinol levels in children after computer tomography
2014, Archives of Biochemistry and BiophysicsCoenzyme Q<inf>10</inf> as an Antioxidant in the Elderly
2014, Aging: Oxidative Stress and Dietary AntioxidantsAnalysis of circulating lipid-phase micronutrients in humans by HPLC: Review and overview of new developments
2013, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life SciencesCitation Excerpt :CoQ10 in its chemically reduced form of ubiquinol-10 (UL10) is considered a free radical scavenger that protects low-density lipoproteins against oxidative stress in vitro [5]. As such, UL10 acts to reduce lipid peroxyl or tocopheroxyl radicals [96] which explains the rapid oxidation of UL10 in plasma [97], and also minimizes oxidative stress by dehydrogenating ubiquinone-10 (UN10), the chemically oxidized form of CoQ [98–105]. Thus, the UL10:UN10 ratio has been postulated as an in vivo marker of oxidative stress [5,106,107], whereas total Q10 (TQ10) may represent general physiological events such as cell death, as dying cells would leak Q10 into the circulation [103,108–110].
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