Neuron
Volume 11, Issue 5, November 1993, Pages 939-949
ArticleA GTPase-accelerating factor for transducin, distinct from its effector cGMP phosphodiesterase, in rod outer segment membranes
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2007, Advances in Protein ChemistryCitation Excerpt :Early studies suggested that PDEγ was a GAP for Gαt (Arshavsky and Bownds, 1992). However, it was later appreciated that PDEγ has no GAP activity on its own, but rather stimulates a photoreceptor membrane‐associated GAP activity three‐ to sixfold (Angleson and Wensel, 1993; Antonny et al., 1993; Arshavsky et al., 1994). The GAP was identified as RGS9, a member of the R7/C family of “complex” RGS proteins (Chen et al., 2000; He et al., 1998).
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