European Journal of Pharmacology: Molecular Pharmacology
Rapid communicationEvidence for adenosine A2b receptors in the rat pineal gland
References (6)
A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding
Anal. Biochem.
(1976)- et al.
Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes
Mol. Pharmacol.
(1986) - et al.
5′-N-Ethylcarboxamidoadenosine stimulates cAMP and N-acetylserotonin syntheses in cultured organ rat pineal
Adv. Pineal Res.
(1991)
Cited by (16)
Characterization of [<sup>125</sup>I]ZM 241385 binding to adenosine A<inf>2A</inf> receptors in the pineal of sheep brain
2006, Brain ResearchCitation Excerpt :NECA has also been shown to stimulate cyclicAMP production and melatonin secretion in cultured chicken pineal cells (Falcon et al., 1995). The actions of NECA to stimulate N-acetylserotonin and melatonin production in rat pinealocytes has more recently been attributed to activation of adenosine A2B receptors based on the pharmacologic profile of adenosine analogs (Nicholls et al., 1997; Gharib et al., 1992), thus rendering ambiguous evidence for adenosine A2A receptor expression and function in mammalian pineal. Autoradiographic labeling of adenosine A2A receptors in the CNS has typically employed radiolabeled versions of agonists such as 5′-N-ethycarboxamidoadenosine ([3H]NECA) (Alexander and Reddington, 1989), 2-[4-(2-carboxyethy)phenothylamino]-5′-N-ethylcarboxamidoadenosine [3H]CGS21680) (Jarvis et al., 1989; Parkinson and Fredholm, 1990; Johansson and Fredholm, 1995) and 4-aminobenzyl-5′-N-methylcarboxamidoadenosine ([125I]AB-MECA) (Shearman and Weaver, 1997).
Caffeine-induced modifications of heart rate, temperature, and motor activity circadian rhythms in rats
1999, Physiology and BehaviorAdenosine A<inf>2</inf> receptor-mediated excitatory actions on the nervous system
1996, Progress in NeurobiologyPurinergic signalling in endocrine organs
2014, Purinergic Signalling