Review articleRemifentanil: A new opioid
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Impact of time interval between remifentanil and propofol on propofol injection pain
2016, Journal of Clinical AnesthesiaCitation Excerpt :TimeRP was defined as the time interval from the initiation of the remifentanil injection to the initiation of the propofol injection. TimeRP for the first patient in each group was 90 seconds because the half-time for equilibration between plasma and its effect compartment (t1/2ke0) is 1.0 to 1.5 minutes [21,22] in the case of remifentanil. TimeRP for each subsequent patient was determined by the response of the previous patient using Dixon's up-and-down method [23].
Greater temperature variability is not associated with a worse neurological outcome after cardiac arrest
2015, ResuscitationCitation Excerpt :Body temperature is initially measured using a rectal temperature probe; in those patients requiring an invasive haemodynamic monitoring device (PiCCO, Pulsion, Munich, Germany), temperature is then recorded using the blood sensor. All patients undergoing TTM receive sedation (midazolam, as a continuous infusion of 0.03–0.1 mg/kg/h) and analgesia (morphine or, in case of renal failure, remifentanil at an equipotent dose of 0.1–0.3 mg/kg/h).19 For shivering control, neuromuscular blocking agents (NMBAs) are administered in the induction phase (cisatracurium as a bolus of 0.15 mg/kg) and, if needed, as a continuous infusion thereafter (1–3 mcg/kg/min).
Considerations for the use of short-acting opioids in general anesthesia
2014, Journal of Clinical AnesthesiaCitation Excerpt :The contraindications and utility of these agents in special populations to decrease side effects would further ensure safe and efficacious use. In particular, the short-acting opioid remifentanil with its rapid onset and offset, decreased accumulation, and easy titration make it an attractive drug for improving the overall patient experience when used in combination with hypnotic agents [53]. Other advantages, in particular with remifentanil, include decreased hemodynamic side effects, and neurohumoral stress response to surgery [66].
Effect of intravenous propofol and remifentanil on heart rate, blood pressure and nociceptive response in acepromazine premedicated dogs
2011, Veterinary Anaesthesia and AnalgesiaInfluence of different remifentanil concentrations on the performance of the surgical stress index to detect a standardized painful stimulus during sevoflurane anaesthesia
2009, British Journal of AnaesthesiaCitation Excerpt :Regarding variables obtained before stimulation, only Ceremi, NIAPsys, and HR but not SSI showed predictive power concerning a defined response, like movement, after stimulation. These findings were expected for Ceremi, as increasing remifentanil concentration reduces MAC.21 Regarding the predictive power of HR and NIAPsys, we suggest that HR and NIAPsys were most probably reduced by increasing Ceremi.
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Associate Professor.