A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates
The synthesis of 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylates (4a-c), highly potent antagonists for a phospholipase C-linked metabotropic glutamate receptor, mGluR1, is described.
References (29)
- et al.
Trends Pharmacol. Sci.
(1993) Neuron
(1994)- et al.
Trends Pharmacol. Sci.
(1994) - et al.
Neuron
(1992) - et al.
Neuron
(1992) - et al.
J. Biol. Chem.
(1992) - et al.
Eur. J. Pharmacol.
(1989) - et al.
Eur. J. Pharmacol.
(1990) - et al.
Brain Res.
(1990) - et al.
Neurosci. Lett.
(1993)
Trends Pharmacol. Sci.
(1990)
Science
(1992)
Annu. Rev. Neurosci.
(1994)
J. Med. Chem.
(1995)
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