Le récepteur H3 de l’histamine : une cible pour de nouveaux traitements des troubles de l’éveil et de la cognitionThe histamine H3 receptor: a new target for the treatment of arousal and cognitive disorders☆
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Cited by (3)
Histaminergic Modulation of Recognition Memory
2018, Handbook of Behavioral NeuroscienceCitation Excerpt :Through extensive cross-talks with other GPCRs, they can also engage Gq/11 signalling and activate PLA2, Akt/GSK3 and MAP kinase pathways, all of which play important roles in axonal and synaptic plasticity and a variety of brain disorders (Haas et al., 2008). The histamine H3R is located on histaminergic neuron somata, dendrites and axon varicosities, as well as on the axon varicosities and somata of other neurons, providing negative feedback to inhibit histamine synthesis and the release of histamine or other transmitters, including glutamate (Brown and Reymann, 1996; Doreulee et al., 2001), acetylcholine (Arrang, 2007; Blandina et al., 1996) and GABA (Jang et al., 2001; Yamamoto et al., 1997). In keeping with their role as autoreceptors and heteroreceptors, H3R are heterogeneously distributed among areas known to receive histaminergic projections (Hu et al., 2007).
International union of basic and clinical pharmacology. XCVIII. histamine receptors
2015, Pharmacological ReviewsRat Merkel cells are mechanoreceptors and osmoreceptors
2009, PLoS ONE
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Présentation devant les Académies nationales de pharmacie et de médecine, lors d’une séance commune, le 29 novembre 2006, à l’École du Val-de-Grâce, Paris.