Research paperEvidence for the shuttle model for GSα activation of adenylyl cyclase☆
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Cited by (9)
Differential expression of adenylyl cyclase subtypes in human cardiovascular system
2004, Molecular and Cellular EndocrinologyRole of G-protein availability in differential signaling by alpha 2-adrenoceptors
2001, Biochemical PharmacologyCitation Excerpt :Increased availability of Gs-proteins should in the case of interaction with the receptor affect the concentration-dependence of stimulation. This has been shown for Gs and β2-AR [28]. Concentration-response relationships for noradrenaline and UK14,304 in cells coexpressing Gs and the α2B-AR are shown in Fig. 4.
Kinetics versus equilibrium: The importance of GTP in GPCR activation
1999, Trends in Pharmacological Sciences
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This work was supported by NIH Grant RR07710.
Copyright © 1997 Published by Elsevier Inc.