Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

doi:10.1016/S0006-8993(99)01428-6

Brain Research

Volume 831, Issues 1–2, 12 June 1999, Pages 288-291

https://doi.org/10.1016/S0006-8993(99)01428-6 Get rights and content

Abstract

In the submucous plexus, double immunocytochemistry revealed that nitric oxide synthase (NOS)-immunoreactivity was found in both numerous nerve fibers and some nerve cell bodies, while 5-hydroxytryptamine (5-HT)-immunoreactivity was limited to many nerve fibers, but not any nerve cell bodies. About 30% of the total NOS positive neurons (978) had close or some contact with 5-HT positive nerve fiber, suggesting that NO may participate in the 5-HT-evoked chloride secretion.

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Acknowledgements

The authors thank Dr. Paul R. Wade (The University of Wyoming) for reviewing the manuscript. This work was supported by Monbusyo International research grant, Salt foundation and Health Science Foundation to AK.

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Short communicationMorphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

Abstract

Section snippets

Acknowledgements

Neuroscience

Neurosci. Lett.

Neuroscience

Neuroscience

Neural 5-hydroxytryptamine receptors regulate chloride secretion in guinea pig distal colon

Am. J. Physiol.

Nitric oxide producing neurons in the monkey and human digestive system

J. Comp. Neurol.

Short communication
Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon