Original articlesGeneration of polyclonal antiserum against the growth hormone secretagogue receptor (GHS-R): Evidence that the GHS-R exists in the hypothalamus, pituitary and stomach of rats
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Palmitic acid activates NLRP3 inflammasome through NF-κB and AMPK-mitophagy-ROS pathways to induce IL-1β production in large yellow croaker (Larimichthys crocea)
2024, Biochimica et Biophysica Acta - Molecular and Cell Biology of LipidsExpressions of ghrelin and GHSR-1a in the corpus luteum and the stimulatory effect of ghrelin on luteal function of pregnant sows
2023, Domestic Animal EndocrinologyA review on ghrelin and fish reproduction
2021, Reproduction and BreedingMechanisms for AgRP neuron-mediated regulation of appetitive behaviors in rodents
2018, Physiology and BehaviorCitation Excerpt :Exogenous ghrelin markedly increases appetitive behaviors and food intake in humans [36], and elevated ghrelin levels underlie, at least in part, pathologies including Prader-Willi Syndrome that are characterized by unrestrained feeding and hoarding of food and food-related objects [37,38]. AgRP neurons strongly express the ghrelin receptor, growth hormone secretagogue receptor 1a (GHSR) [29,39,40], and selective GHSR reexpression on these neurons in otherwise ghsr−/− mice restores ghrelin's orexigenic effects [41]. Hence, ghrelin has become an important target for pharmacological intervention to combat obesity, and blockade of ghrelin-induced AgRP activation may prevent acute and/or chronic increases in appetitive behaviors following energetic challenges.
Regulation of food intake
2018, Encyclopedia of Endocrine DiseasesDriving the need to feed: Insight into the collaborative interaction between ghrelin and endocannabinoid systems in modulating brain reward systems
2016, Neuroscience and Biobehavioral Reviews