Central and peripheral benzodiazepine receptors: Involvement in an organism's response to physical and psychological stress
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A higher inherent trait for fearfulness is associated with increased anxiety-like behaviours and diazepam sensitivity in Japanese quail
2013, Behavioural Brain ResearchCitation Excerpt :To test whether LTI and STI quails might represent a valuable bird model for studying anxiety, we assessed the behavioural effects of intraperitoneal injections of diazepam, a standard anxiolytic drug, to both STI and LTI birds in the open field and the tonic immobility tests. Diazepam is a classical benzodiazepine that binds to a central benzodiazepine receptor increasing the effects of the γ-aminobutiric acid (GABA), with an anxiolytic effect mediated by the enhancement of chloride conductance [24]. Diazepam has been used in many species including birds and shown to reduce fear or anxiety related behaviours [8].
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