Current awareness
Cloning of human prostanoid receptors

https://doi.org/10.1016/S0165-6147(00)89035-5Get rights and content

First page preview

First page preview
Click to open first page preview

References (23)

  • M. Abramovitz

    J. Biol. Chem.

    (1994)
  • Y. Boie

    J. Biol. Chem.

    (1994)
  • C.D. Funk

    J. Biol. Chem.

    (1993)
  • L. Bastien et al.

    J. Biol. Chem.

    (1994)
  • A. Honda

    J. Biol. Chem.

    (1993)
  • N. Nishigaki

    FEBS Lett.

    (1995)
  • Y. Sugimoto

    J. Biol. Chem.

    (1993)
  • R.M. Breyer

    J. Biol. Chem.

    (1994)
  • R.J. Lefkowitz

    Cell

    (1993)
  • M. Negishi et al.

    J. Biol. Chem.

    (1993)
  • M.K. Raychowdhury

    J. Biol. Chem.

    (1994)
  • Cited by (79)

    • Pharmacology and perspectives in erectile dysfunction in man

      2020, Pharmacology and Therapeutics
      Citation Excerpt :

      TXA2 and PGF2α, through the activation of the TP or FP receptor, and PGE, through EP1 and EP3, mediate the contraction of erectile tissue (Angulo et al., 2002). PGD2, PGE, and PGI2 can induce smooth muscle relaxation (Pierce, Gil, Woodward, & Regan, 1995). The major relaxing prostanoid in corpus cavernosum smooth muscle is PGE (PGE1 and PGE2), which induces relaxation by binding to G-protein-coupled receptors (EP2-EP4) and by increasing cAMP synthesis (Lue & Dahiya, 1997).

    • Pharmacology of erectile dysfunction in man

      2006, Pharmacology and Therapeutics
    • Comparison of prostaglandin F<inf>2α</inf>, Bimatoprost (prostamide), and Butaprost (EP<inf>2</inf> agonist) on Cyr61 and connective tissue growth factor gene expression

      2003, Journal of Biological Chemistry
      Citation Excerpt :

      Activation of FP receptors initiated by ligand binding triggers Gαq protein-coupled mechanisms involved intracellular Ca2+ signaling, IP turnover, and activation of protein kinase C (28). Butaprost is a synthetic prostaglandin analog that interacts with EP2 receptors; it triggers Gαs protein-coupled mechanisms involved in activation of adenylate cyclase and initiation of the cAMP pathway with resultant activation of protein kinase A (29). Despite different intracellular mechanisms, it has been shown that activation of prostaglandin FP or EP2 receptors resulted in lowering intraocular pressure (15, 16).

    View all citing articles on Scopus
    View full text