Review
CD6—ligand interactions: a paradigm for SRCR domain function?

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Abstract

The scavenger receptor cysteine-rich (SRCR) superfamily which includes proteins expressed by leukocytes, can be subdivided into groups A and B. Group B contains the lymphocyte cell-surface receptor CD6. This article reviews recent progress in understanding the interaction between CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM). Analysis of the CD6-ALCAM interaction may help to understand how other SRCR domains bind to their ligands.

References (44)

  • D. Resnick et al.

    Trends Biochem. Sci.

    (1994)
  • M. Emi et al.

    J. Biol. Chem.

    (1993)
  • T.J. Vyse et al.

    Genomics

    (1994)
  • J. Gebe et al.

    J. Biol. Chem.

    (1997)
  • W.E. Mayer et al.

    Gene

    (1995)
  • X. Li et al.

    J. Biol. Chem.

    (1995)
  • J.D. Peduzzi et al.

    Brain Res.

    (1994)
  • M.A. Bowen et al.

    J. Biol. Chem.

    (1996)
  • G.S. Whitney et al.

    J. Biol. Chem.

    (1995)
  • S. Wee et al.

    Cell. Immunol.

    (1994)
  • T. Kodama et al.

    Nature

    (1990)
  • A. Tarakhovsky et al.

    Eur. J. Immunol.

    (1994)
  • M.A. Bowen et al.

    J. Immunol.

    (1997)
  • N.H. Jones et al.

    Nature

    (1986)
  • A. Aruffo et al.

    J. Exp. Med.

    (1991)
  • P.L. Wijngaard et al.

    J. Immunol.

    (1992)
  • S.K.A. Law et al.

    Eur. J. Immunol.

    (1993)
  • H. Cheng et al.

    Anat. Rec.

    (1996)
  • J. Takito et al.

    J. Clin. Invest.

    (1996)
  • D.P. Nunes et al.

    Biochem. J.

    (1995)
  • H. Van de Velde et al.

    Nature

    (1991)
  • L. Biancone et al.

    J. Exp. Med.

    (1996)
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