Elsevier

Drug Discovery Today

Volume 8, Issue 7, 1 April 2003, Pages 281-282
Drug Discovery Today

Update
Improving drug response with pharmacogenomics

https://doi.org/10.1016/S1359-6446(03)02650-3Get rights and content

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A new curriculum

‘The need to incorporate the teaching of pharmacogenomics into the medical curriculum is quite urgent,’ said Gurwitz, who this academic year has launched such a course at Tel-Aviv University, which he hopes will stimulate other medical schools to follow. must be incorporated within a few years... into the general MD curriculum,’ he said.

The consequence of not doing so, he says, could be that any therapeutic benefits of the Human Genome Project will be severely delayed. The next generation of

Advanced pharmacogenomics

Physicians regularly practice rudimentary pharmacogenomics by asking patients for their family histories of drug sensitivity. More advanced DNA-based pharmacogenomics is already a feature of chemotherapy, where genetic analysis of cancer tissue helps oncologists choose a drug regime that will attack tumour cells most effectively.

Many genes have also been identified that have an effect on drug receptors and metabolism, says Katie Prickett, Commissioning Editor of Pharmacogenomics. ‘CYP2D6 and

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