Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1843, Issue 12, December 2014, Pages 2976-2988
ReviewRal small GTPase signaling and oncogenesis: More than just 15 minutes of fame
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Abbreviations
CAAX
cysteine-aliphatic-aliphatic-terminal amino acid
DMBA
7,12-dimethylbenz[α]anthracene
EGF
epidermal growth factor
EH
Eps homology
ER
endoplasmic reticulum
GAP
GTPase activating protein
GEF
guanine nucleotide exchange factor
ICMT
isoprenylcysteine carboxyl methyltransferase
NSCLC
non-small cell lung cancer
PDAC
pancreatic ductal adenocarcinoma
PH
pleckstrin homology domain
PKA
protein kinase A
PKC
protein kinase C
RA
Ras-association domain
RBD
Ral-binding domain
RCE1
Ras converting enzyme 1
REM
Ras exchanger motif
SI/II
SwitchI/II
SCC
squamous cell carcinoma
SH3
Src homology 3 domain
Keywords
Exocyst
GTPase activating protein
Guanine nucleotide exchange factor
Ras
Rho
Small GTPase
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