Biphenyl-indanones: Allosteric potentiators of the metabotropic glutamate subtype 2 receptor
Graphical abstract
The metabotropic glutamate receptor 2 has been implicated in a number of central nervous system disorders. Herein, we report on the discovery, synthesis, and biological evaluation of biphenyl-indanones as potent small molecule mGluR2 allosteric modulators.
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