Asthma and lower airway diseaseTiotropium modulates transient receptor potential V1 (TRPV1) in airway sensory nerves: A beneficial off-target effect?⋆
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M.A.B., S.A.M., and M.S.G. were funded by project grants from the Medical Research Council (MRC UK: G0800196; G0800195; MR/K020293/1). S.J.B. and M.A.W. were supported by NHLI Trust and MRC studentships, respectively. E.D. was funded by a Wellcome Trust project grant (089301/Z/09/Z) and latterly by a research grant from Boehringer-Ingelheim. Consumables were funded by Boehringer-Ingelheim. The human tissue experiments in this study were undertaken with the support of the NIHR Respiratory Disease Biomedical Research Unit at the Royal Brompton and Harefield NHS Foundation Trust and Imperial College London.
Disclosure of potential conflict of interest: M. G. Belvisi has received research support from Boehringer Ingelheim; has received support for travel to the 2012 ERS meeting; is a Director of IR Pharma CRO; has received consultancy fees from Chiesi, Glenmark, Almirall, AstraZeneca, GlaxoSmithKline, SunPharma, Provesica, Ario, and Innosquared; and has received lecture fees from Chiesi. The rest of the authors declare that they have no relevant conflicts of interest.